Letrozol SUN 2,5 mg

5,34 53,40 

SKU: N/A Category:

Description

Composition

  • Active substance: letrozole;
  • 1 film-coated tablet contains 2.5 mg letrozole;
  • excipients: lactose, maize starch, hypromellose, microcrystalline cellulose, sodium starch (type A), colloidal silicon dioxide, magnesium stearate.
  • Coating: hypromellose, titanium dioxide (E 171), iron oxide yellow (E 172), polyethylene glycol 400, talc, purified water.
  • Dosage form: film-coated tablets.
  • Main physicochemical characteristics: round, biconvex, smooth on both sides yellow film-coated tablets.

Pharmacological group

Agents used in hormonal therapy. Hormone antagonists and similar agents. Aromatase inhibitors. Letrozole.

Pharmacological properties

Letrozole is a non-steroidal aromatase inhibitor (estrogen biosynthesis inhibitor) with anti-tumour activity.

In cases where the growth of tumour tissue depends on the presence of oestrogens, elimination of the stimulating effect of oestrogens is a prerequisite for inhibition of tumour growth. In postmenopausal women, estrogens are mainly formed by the enzyme aromatase, which converts androgens synthesised in the adrenal glands (mainly androstendione and testosterone) into estrone (E1) and estradiol (E2). Therefore, by specifically inhibiting the aromatase enzyme, inhibition of estrogen biosynthesis in peripheral tissues and tumour tissue can be achieved.

Additional information

substance active

letrozole

Amount of substance, mg

2.5

formulaire de discharge

compressed

1 compressed, mg

2.5

Plaquettes thermoformed by package, pieces

dix

manufacturer

Sun Pharmaceuticals Germany GmbH

volume de commande

1 blister of 10 compresses, 1 pack (3 blisters), 1 package (10 blisters), 1 packet (6 blisters)

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